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September 2011

The tiny white yeast colonies in the right panel interspersed with larger normal colonies are cells that have had a synthetic chromosome inserted and their DNA shuffled by the lab-induced SCRaMbLE system, which introduces changes that slow cell growth. By comparison, all colonies on the left are grown from the standard lab yeast strain and appear uniform. (Click on image to enlarge.)

Designer yeast

September 14th, 2011 Updated: November 30th, 2011

A Johns Hopkins University team has built a yeast chromosome from scratch, they report today in the journal Nature. Sarah Richardson used what she learned as a Computational Science Graduate Fellow to help design and monitor the chromosome’s construction.

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Boosting Berkeley Lab’s bacteria research

September 14th, 2011 Updated: November 30th, 2011

For one summer, Sarah Richardson postponed her work computerizing yeast genome research and probed bacteria instead. As part of her Department of Energy Computational Science Graduate Fellowship, Richardson served a 2009 practicum under Adam Arkin, director of Lawrence Berkeley National Laboratory’s Physical Biosciences Division. She made important contributions to Arkin’s research into an RNA-based transcription [...]

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